Cure Childhood Cancer

Current Research Initiatives

And the research continues. This fiscal year we are allocating $2.5 million in Pediatric Research Grants and Fellowships to support scientists at:

  • The Aflac Cancer Center and Blood Disorders Center of Children’s Healthcare of Atlanta
  • Emory University
  • MD Anderson Cancer Center
  • Children’s Hospital of Philadelphia
  • Seattle Children’s Hospital
  • Memorial Sloan Kettering Cancer Center

For fiscal year 2014-2015, CURE is supporting 20 specific projects, most of which focused on finding effective treatments for the 20% of kids who do not survive childhood cancer.

Click here to view a report on the research funded during fiscal year 2014-2015. Check back for a more detailed report on the research funded during fiscal year 2014-2015.

Researcher(s): Area of Study: Research Summary:



Dr. Kenney Medulloblastoma Targeting medulloblastoma growth and radiation resistance: gene expression and DNA-repair.
Dr. Gu Neuroblastoma Targeting MDM2 and MYCN for anti-neuroblastoma drug discovery.
Dr. Spencer Lymphocyte Leukemia Generation of Anti-cancer CARs by Lamprey-Generated Variable Lymphocyte Receptors.
Dr. Zhou Acute Lymphoblastic Leukemia Development of novel AQ compounds as a molecularly-targeted and safe treatment for pediatric ALL.
Dr. Goldsmith Neuroblastoma Identification of novel therapeutics to restore chemotherapy response in high-risk neuroblastoma.
Dr. Van Meir Medulloblastoma Targeting H3K27me3-mediated BAI1 silencing for medulloblastoma treatment.
Dr. Wang
Dr. Bunting
Acute Lymphoblastic Leukemia The significance of AF1q in Pediatric Acute Lymphoblastic Leukemia.
Dr. Pauly Acute Myeloid Leukemia A Phase 1 study of of Dastinib in combination with chemotherapy for relapsed or refractory core binding factor acute myeloid leukemia.
Dr. Qayed A Phase 1 study of mesenchymal stromal cells for treatment of acute and chronic graft versus hosts disease.
Dr. Gilleland and Karen Wasilewski-Masker Survivorship Assessing physical activity and quality of life among pediatric cancer survivors.
Dr. Castellino Brain Tumors Mechanisms of PPM1D in growth and treatment responsiveness of pediatric DIPGs.
Dr. Kleinerman Osteosarcoma Combining NK Cell Therapy and Aerosol IL-2 for relapsed osteosarcoma.
Dr. Aplenc Acute Myeloid Leukemia Evaluating Mitchondrial DNA and the role of its variation in the risk of relapse and toxicity in children with AML.
Dr. Hogarty Neuroblastoma Therapy Resistance in Neuroblastoma.
Dr. Kean Rheumatoid Arthritis Abatacept Phase II clinical trial.
Dr. Zhang Neuroblastoma PET Imaging of Glutamine Accumulation in MYCN-amplified neuroblastoma.
Dr. Valerio
Dr. Armstrong
Acute Leukemia Combinatorial Targeting of Epigenetic Mechanisms in MLL- rearranged Acute Leukemia.
Dr. Jonathan Metts
Dr. Siegel
 CURE fully funds two pediatric oncology fellows at the Emory University School of Medicine.
Connolly Family Fellowship Endowment
“CURE is extremely pleased to be partnering with these scientists to continue our search
for cures and better treatments for children with cancer and to improve the quality of life of childhood cancer survivors. CURE has a 39-year-long history of supporting promising research, and we are proud to continue that effort.”
- Kristin Connor, Executive Director

 

 

 

 

 

 

 

 

 

 

 

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